In this five-part blog series, Alice Limonciel explores the role of metabolomics in 5P medicine. In this 3rd article she explores how metabolomics is driving real-world applications of precision medicine, especially in predictive diagnostics, treatment optimization, and personalized nutrition. Learn why sex-based data stratification is essential, how metabolic profiles reveal hidden disease subtypes, and why the future of medicine is personal.
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Propionic acid – A short-chain fatty acid with big impact
A short-chain fatty acid produced by gut, it plays a role in energy metabolism, immune regulation, and neurological health
Predictive medicine – Transform medicine with metabolomics – part 2 of 5
In this five-part blog series, Alice Limonciel explores the role of metabolomics in 5P medicine. This second installment highlights how screening samples with broad metabolomics panels and leveraging data with knowledge-driven tools leads to the translation of metabolomics insights into innovative strategies for predictive medicine.
Preventive medicine – Transform medicine with metabolomics – part 1 of 5
This is the first in a series of five blogs where Alice Limonciel discusses how metabolomics is set to transform medicine as we know it. The applications of omics in biomedical research are vast, and to help organize the different ways metabolomics can be used, I’ll discuss this in the context of 5P medicine.
mGWAS – Integrating metabolomics in genome-wide association studies for more precise results
Combining genome-wide association studies (GWAS) with metabolomics and Mendelian randomization is transforming precision medicine by uncovering causal links between genetic variants and clinical outcomes, rather than just correlations.
3 words to capture Metabolomics 2024
ASMS 2024, a main event for the mass spectrometry community, showcased the latest advancements in mass spectrometry and fostered important collaborations in the field of metabolomics.
Mass spectrometry in metabolomics – From methodologies to applications
Metabolomics highlights the significant role of microbial communities in human health, driving a paradigm shift towards towards personalized, proactive healthcare.
Does metabolomics have a place in microbiome research?
Metabolomics highlights the significant role of microbial communities in human health, driving a paradigm shift towards towards personalized, proactive healthcare.
p-cresol sulfate – A key uremic toxin with implications for gut health and chronic disease
The metabolite of this month is p-cresol sulfate, a sulfate conjugate of the bacterial metabolite p-cresol, which is a uremic toxin.
Alpha-pinene – The terpene with powerful anti-inflammatory and respiratory benefits
As one of the metabolites responsible for the smell of conifers, alpha-pinene is a fitting choice for our festive Metabolite of the month.
Cinnamaldehyde – The bioactive compound with potent anti-inflammatory and antioxidant properties
In our metabolite of the month series, our scientists look at one specific metabolite each month. Topics of discussion include the biosynthesis and degradation in a broader health context, and the effect of dysregulation. In this month´s article, they took a closer look at Cinnamaldehyde.
3 assets needed to excel at metabolomics data interpretation
Data interpretation is often overlooked in omics training. But without knowing how to make sense of our results in the...
Phosphatidylethanolamines – Key lipids in cellular function and membrane integrity
Phosphatidylethanolamine (PE) is a sub-class of phospholipids with a variety of functions in animals, plants and microorganisms. Like other phospholipids, PEs are more than simply the building blocks of membranes
Metabolite – 3-Hydroxy Glutaric Acid (A biomarker for a rare disease)
3-hydroxyglutaric acid is a little known metabolite with great application for the diagnosis of a rare disease.
NAD+ (nicotinamide adenine dinucleotide) – Metabolite of the month
NAD is best known as a master regulator of redox reactions, but it is also a substrate used by many enzymes to fine tune cell biology.
Metabolomics 2022 in person
In this article we share our take-aways and experience from Metabolomics 2022 in Valencia. We summarized not only exciting talks, posters and trends but also the thrill of meeting with the metabolomics community in person again.
Asymmetric dimethyl arginine (ADMA) – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. Topics of discussion include the ..
The Metabolomist
The Metabolomist is a podcast for metabolomics researchers to connect with like-minded scientists and explore the unspoken issues in metabolomics research.
Sphingomyelins – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at sphingomyelins, building blocks of eukaryotic cell membranes, play in cell signaling, growth, and survival.
Metabolomics unravels aspects of Alzheimer’s disease
Metabolites and genetic markers help to enlighten aspects of Alzheimer’s disease
Are effects of antibiotics reflected in the metabolome?
Antibiotics influence the gut microbiome and the plasma or fecal metabolome depending on the class of antibiotics and the gut bacterial composition.
Triglycerides – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at Triglycerides, complex molecules used ..
Metabotypes applied to dairy production
Metabotypes help categorize dairy cows with different lactation yields
MetaboINDICATOR™
MetaboINDICATOR™ - Translate metabolomics & lipidomics into knowledge Making the most of metabolomics data Alice...
New analytical method for the quantification of acylcarnitines
Acylcarnitine profiles of melanoma xenografts in mice could be a step towards a new treatment.
Metabolite of the month – Dopamine
Metabolite of the month is your sneak peek into the world of metabolomics. This month discover dopamine, a link between memory, blood pressure, and music.
Modulating gut microbiota with prebiotics could control type 2 diabetes
Modulation of gut microbiota with prebiotic Fructooligosaccharides (FOS) led to discovery of two novel enterosynes (12-HETE and enkephalin), with potential to control type 2 diabetes
Spermidine : Unlocking the secrets of cellular aging and longevity
The metabolite of this month is spermidine, a biogenic amine with applications in cancer, neurology and hair research.
Cholic acid – a signaling molecule
The metabolite of this month is cholic acid, of the the bile acid class. Notorious for their role in digestion, they are also powerful regulators of metabolism.
Arachidonic acid – Essential fatty acid with key roles in inflammation and cell signaling
The metabolite of this month is arachidonic acid, a polyunsaturated fatty acid at the crossroads between inflammation, athlete training and the latest COVID-19 research.
Kynurenine – Metabolite of the month
Kynurenine is a tryptophan-derived metabolite at the crossroads between neurology, immunology and cancer
Carnitine – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. This month we look at carnitine #loveyourmetabolites
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