Biocrates® Bile Acids Kit
The benchmark solution to assess host-microbiota interaction
Bile acids are produced in the liver and are best known to facilitate the absorption of dietary fats and fat-soluble vitamins. Beyond this, bile acids exert important signaling and regulatory functions via nuclear receptors such as the farnesoid X receptor (FXR). Since gut bacteria convert primary into secondary bile acids, they are essential to study the role of gut microbiota in health and disease.
The Biocrates® Bile Acids kit is the first ready-to-use, standardized solution for the quantitation of 20 bile acids by liquid chromatography-mass spectrometry (LC-MS).
All in one box
- Includes all necessary reagents and methods
High throughput
- Up to 400 samples per instrument per week
Proven reproducibility
- Excellent inter-laboratory comparability proven in international ring trial
Superior data quality
- Outstanding accuracy and precision of results
Kit components
Reagents & consumables
- Patented 96-well filter plate
- Internal & calibration standards
- Quality controls
- Testmix
Methods & protocols
- Sample preparation protocol
- Instrument-specific acquisition & quantification methods
- System suitability test
Workflow manager MetIDQ™
- Process guidance
- Automated technical validation
- Basic statistics (optional)
Covered bile acids
10 primary bile acids: produced by the liver (CA, GCA, TCA, CDCA, GCDCA, TCDCA, α-MCA, β-MCA, ω-MCA, TMCA(α+β))
10 secondary bile acids: produced by gut bacteria from primary bile acids (DCA, GDCA, TDCA, LCA, GLCA, TLCA, UDCA, GUDCA, TUDCA, HDCA)
For Research Use Only. Not for use in diagnostic procedures.