With more than 20 hours of cutting-edge science in the rearview mirror, it’s time to reflect on our recent “Pan-cohort studies – The future of population health” event.
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Epidemiology is the study of the distribution and determinants of health and disease conditions in populations. It is a vital science branch of public health that helps us understand the patterns and causes of health problems and how they can be prevented.
The 8th Munich Metabolomics Symposium
Recap of the 8th Munich Metabolomics Symposium, November 12th, 2021
Cholesterol metabolism in Alzheimer’s disease
Brain cholesterol metabolism is altered in Alzheimer’s Disease.
Alterations in metabolism might cause chronic kidney disease
Chronic kidney disease and impaired renal function shown to be associated with a variety of metabolites, suggesting the involvement of several metabolic pathways in the disease pathophysiology.
Effect of proton pump inhibitor use on development of cardiovascular diseases
Population-based cohort study reveals link between proton pump inhibitor intake and increasing risk for cardiovascular events.
Multi-omics reveals new insights into chronic malarias
Host-parasite interactions in chronic and acute malaria were characterized by metabolomics and transcriptomics in macaques and humans.
Defining the biochemistry of obesity
Increasing degree of metabolic dysregulation visible in the blood metabolome depending on the degree of obesity.
Prenatal PFAS exposure leads to liver injuries in children
HELIX metabolomics study links prenatal PFAS (perfluoralkyl substances) exposure to metabolic origin of liver injuries in children.
Commentary – A current view on steroid hormones
Although they are only present in low concentration in our bodies, steroid hormones play a crucial role in a variety of biological processes. This article reflects recent studies on the topic.
Blood-based score objectively captures dietary patterns
A blood-based predictive metabolomics score provides a tool linking dietary patterns to risk of diabetes that can be used to objectively assess dietary intake.
Microbiome instability and host metabolic dysfunctions
Plasma metabolome and microbiota profiles from the SHIP cohort link microbiome instability to liver steatosis, diabetes mellitus, and pancreatic dysfunction
Pan-Cohort Metabolomics – The future of population health
Epidemiological research contributes greatly to our understanding of what constitutes healthy aging. Cohort studies hold the key to identifying risk factors for common diseases. Metabolomics is a valuable tool to make cohort studies successful.
Circulating metabolites predict coronary heart disease risk
Serum metabolites were associated with risk of coronary heart disease in a population-based cohort, with a comparable strength to classic risk factors.
The metabolic cost of a marathon: fitness matters
Targeted metabolomics reveals differences in metabolic profiles between top athletes and amateur runners days after running a marathon.
Does metabolic syndrome manifest itself differently?
An international team of scientists applied targeted metabolomics to deepen the mechanistic understanding of metabolic syndrome and its regional specificities.
Which metabolites tell your diet?
Uncovering the mechanism linking the Mediterranean diet with reduced risk for cardiometabolic diseases using targeted metabolomics.
A metabolic profile of all-cause mortality risk
To predicting life expectancy standardized and reproducible scientific methods are needed. Metabolomics is one way to approach this question.