MxP® Quant 500 XL kit

Unraveling the complexity of disease

The MxP® Quant 500 XL offers the largest combination of lipids and small molecules for targeted metabolic profiling in a single kit. Powered by biocrates’ standardized, quality-controlled, and reproducible metabolomics technology, the ready-to-use kit covers more than 1,000 metabolites from various biochemical classes. With more than 400 quantifiable metabolism indicators, covering hundreds of metabolic pathways, researchers will be equipped with the right solution for a more comprehensive understanding of health and disease.

MxP Quant 500 XL
MxP Quant 500 XL

MxP® Quant 500 XL

Unraveling the complexity of disease

The MxP® Quant 500 XL offers the largest combination of lipids and metabolites for targeted metabolic profiling in a single kit. Powered by biocrates’ standardized, quality-controlled, and reproducible metabolomics technology, the ready-to-use kit covers more than 1,000 compounds from various biochemical classes. With more than 400 quantifiable metabolism indicators, covering hundreds of metabolic pathways, researchers will be equipped with the right solution for a more comprehensive understanding of health and disease.

Extensive pathway coverage

  • Quantifies up to 1,019 metabolites from 39 biochemical classes from minimal sample amounts
  • Enables study hundreds of relevant pathways with over 400 metabolism indicators
  • Provides a profound functional understanding of lipid and metabolite homeostasis
Functional-Microbiomics_Mikroben

Deciphering disease complexity

  • Includes hundreds of metabolites related to healthy aging and neurodegenerative diseases
  • Expands coverage of cardiometabolic diseases including metabolism of non-alcoholic fatty liver (NAFLD) and cardiovascular disease (CVD)
Ready-to-use_Kitbox

Easy and ready-to-use

  • Complete workflow from sample registration to data generation
  • No need for method development or optimization
  • Requires only 20 µL sample volume, applicable to various matrices
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Quantitative and reproducible

  • Quantification based on internal standards and calibration curves
  • Standardized, quality controlled, and optimized for longitudinal studies
  • Proven high accuracy and reproducibility through cross-lab validation
MxP-Quant-500-kit

Kit components

Reagents and consumables
  • Patented 96-well filter plates with pre-set internal standards
  • Calibration standards and quality controls
  • Test samples for system suitability test
Methods and protocols
  • Quick-start guide and user manual
  • Sample preparation protocol
  • Instrument-specific methods

Kit requirements

WebIDQ™ – Workflow manager
  • Cloud-based software (on-premise option also available)
  • Complete experimental process guidance
  • Automated quantification, technical validation and report generation
  • MetaboINDICATOR™ with more than 400 biologically relevant metabolite sums and ratios
LC column and MS systems
  • Compatible with Agilent 6495 C, SCIEX 5500, 5500+, and Waters TQ-XS
  • Validated column system
  • Compatible with ultra high performance liquid chromatography (UHPLC)

Quantitative analysis of up to 1,019 metabolites from 39 biochemical classes

Metabolite coverage

Small molecules
  • Alkaloids (1)
  • Amine oxides (1)
  • Amino acids (20)
  • Amino acid related (30)
  • Bile acids (14)
  • Biogenic amines (9)
  • Carbohydrates and related (1)
  • Carboxylic acids (7)
  • Cresols (1)
  • Fatty acids – Free/non-covalently bound (12)
  • Hormones and related (4)
  • Indoles and derivatives (4)
  • Nucleobases and related (2)
  • Vitamins and cofactors (1)
Polar Lipids
  • Phosphatidic acids (41)
  • Lysophosphatidic acids (8)
  • Phosphatidylcholines (76)
  • Lysophosphatidylcholines (14)
  • Phosphatidylethanolamines (95)
  • Lysophosphatidylethanolamines (43)
  • Phosphatidylglycerols (64)
  • Lysophophatidylglycerols (10)
  • Phosphatidylinositols (53)
  • Lysophosphatidylinositols (16)
  • Phosphatidylserines (18)
  • Lysophosphatidylserines (12)
  • Sphinganines and sphingosines (8)
  • Sphinganine and sphingosine phosphates (8)
  • Sphingomyelins (15)
  • Ceramides (29)
  • Dihydroceramides (8)
  • Hexosylceramides (19)
  • Dihexosylceramides (9)
  • Trihexosylceramides (6)
Neutral lipids
  • Acylcarnitines (40)
  • Cholesteryl esters (22)
  • Monoglycerides (12)
  • Diglycerides (44)
  • Triglycerides (242)

MetaboINDICATOR™ – MxP® Quant 500 XL kit

Translate metabolomics into knowledge with one click

Calculating and understanding metabolite sums and ratios makes your biological data interpretation easier and more comprehensive. That is why we created  MetaboINDICATOR™ as an add-on tool to WebIDQ. With one click you can find out how metabolite sums and ratios are associated with related biological functions so your data has meaningful impact.

MetaboINDICATOR™ is more than an additional dimension to your data analysis; it unravels the scientific context behind your data. All in one click.

Sharpen-Data-Quality_Boxplot

Sharpen your data quality

  • Increase confidence by higher statistical power
  • Find subtle differences between groups
  • See patterns in the data you missed before
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Expand your data readout

  • Use over 400 predefined sums and ratios
  • Create your own metabolism indicators and include them in your analysis
  • Unravel relations between metabolite concentrations
Global-Network-Netz

Advance pathway interpretation

  •  Access underlying enzyme activities
  •  Study relevant pathways instead of metabolites
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Let your data tell the story

  • Established institutional knowledge
  • Access scientific references in one click
  • Supports biomedical interpretation

Is this the right kit for my instruments and applications?

For research use only | not for use in diagnostic procedures.

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