Plasma metabolome and microbiota profiles from the SHIP cohort link microbiome instability to liver steatosis, diabetes mellitus, and pancreatic dysfunction
Microbiome instability and host metabolic dysfunctions
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Hepatology
Bile acids and newborn’s gut microbiota maturation
The maturation of the newborn´s microbiome is critically dependent on bile acids from liver and can be manipulated by administration of bile acids in mice.
Elevated serum bile acid levels contribute to NASH-HCC
Higher serum bile acid levels and an altered gut microbiome contribute to fibrogenesis, liver injury, and tumorigenesis in cirrhotic and noncirrhotic NASH-HCC.
Betaine for a healthy life and brain?
Betaine supplementation has a profound effect on phospholipid metabolism. Its effect on brain and liver health can be studied using targeted metabolomics.