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Hepatology is the branch of medicine that focuses on the liver. This organ is responsible for a variety of important functions, including filtering toxins from the blood, producing bile, and storing glucose. In several pathologies, the liver can also be the place of large fat storage associated with metabolic diseases.
Phosphatidylethanolamine (PE) is a sub-class of phospholipids with a variety of functions in animals, plants and microorganisms. Like other phospholipids, PEs are more than simply the building blocks of membranes
Anti-TNF α therapy in Crohn´s Disease improves liver steatosis through changes in gut bacteria and triglycerides.
New study demonstrates the power of metabolomics in boosting our understanding of fatty liver disease – and possible treatments. Obeticholic acid reverses metabolic changes in NASH.
Elevated liver fat is related to hyperglucagonaemia, which reflects the disruption of the liver-α cell axis.
HELIX metabolomics study links prenatal PFAS (perfluoralkyl substances) exposure to metabolic origin of liver injuries in children.
Plasma metabolome and microbiota profiles from the SHIP cohort link microbiome instability to liver steatosis, diabetes mellitus, and pancreatic dysfunction
The maturation of the newborn´s microbiome is critically dependent on bile acids from liver and can be manipulated by administration of bile acids in mice.
Higher serum bile acid levels and an altered gut microbiome contribute to fibrogenesis, liver injury, and tumorigenesis in cirrhotic and noncirrhotic NASH-HCC.
Betaine supplementation has a profound effect on phospholipid metabolism. Its effect on brain and liver health can be studied using targeted metabolomics.
