MxP® Quant 500 Kit

Metabolomics in nutrition, microbiota, and disease

MxP® Quant 500 is our most comprehensive kit for targeted metabolic profiling. With a coverage of up to 630 metabolites from 26 biochemical classes, this kit brings advanced and reproducible metabolomics technology to academic and clinical researchers. The kit offers fast turnaround times and reliable quantification of a broad range of metabolites. This includes substances related to nutrition and host- microbiota interaction to ensure innovative scientific findings with sustainable impact.

Unique pathway coverage

  • Up to 630 metabolites from 26 biochemical classes quantified from 10 µL sample
  • Study relevant pathways with over 230 sums and ratios

Functional microbiomics

  • Includes dozens of metabolites known to be ­synthesized and modulated by microbiota
  • Provides profound functional understanding about host-microbiota interaction

Ready-to-use

  • Fully integrated workflow
  • No method development required
  • Implementation in less than 2 days

Quantitative & reproducible

  • Automated signal identification and quantification
  • Designed for use with biofluids (serum, plasma, …), suitable for use with fecal samples
  • Up to 240 samples per week per instrument

Kit components

Reagents & consumables

  • Patented 96-well filter plate
  • Calibration standards
  • Quality controls
  • Test sample

Methods & protocols

  • Sample preparation protocol
  • Instrument-specific acquisition & quantification methods
  • System suitability test

Workflow manager MetIDQ

  • Process guidance
  • Automated quantification and ­technical validation
  • Improved data analysis
  • Basic statistics (optional)
  • MetaboINDICATOR

Application: Functional microbiomics and foodomics

Unraveling the interaction of lifestyle, microbiota, metabolism, and health

Investigations of the gut-liver, gut-heart, and gut-brain axis have become of increased interest as researchers become to understand the role of the microbiota and its effect on many organ systems. As metabolic profiles can be obtained from biofluids, metabolomics can provide information about microbiota-related processes where metagenomics studies may not be possible.

The MxP® Quant 500 includes ­microbiota-derived secondary bile acids, which have different signaling properties than primary bile acids that are synthetized by the liver.

Quantitative analysis of up to 630 metabolites from 26 analyte classes

Metabolite coverage

Small molecules

  • Alkaloids (1)
  • Amine oxides (1)
  • Amino acids (20)
  • Amino acid related (30)
  • Bile acids (14)
  • Biogenic amines (9)
  • Carbohydrates and related (1)
  • Carboxylic acids (7)
  • Cresols (1)
  • Fatty acids (12)
  • Hormones (4)
  • Indoles and derivatives (4)
  • Nucleobases and related (2)
  • Vitamins and cofactors (1)

Lipids

  • Acylcarnitines (40)
  • Phosphatidylcholines (76)
  • Lysophosphatidylcholines (14)
  • Sphingomyelins (15)
  • Ceramides (28)
  • Dihydroceramides (8)
  • Hexosylceramides (19)
  • Dihexosylceramides (9)
  • Trihexosylceramides (6)
  • Cholesteryl esters (22)
  • Diglycerides (44)
  • Triglycerides (242)
Find out the metabolites and lipids covered by the MxP® Quant 500 kit.
For more detail on our lipidomics measurements, read our note on isobaric and isomeric lipid species analyzed with the MxP® Quant 500 kit

MetaboINDICATOR™

Translate metabolomics into knowledge

Calculating and understanding metabolite sums and ratios can make your biological data interpretation easier and more comprehensive. That is why we created the MetIDQ™ software add-on tool MetaboINDICATOR™. Give your data meaningful impact and find out how metabolite sums and ratios are associated with related biochemical pathways.

MetaboINDICATOR™ is more than an additional dimension to your data analysis; it unravels the scientific context behind your data. All in one click.

Sharpen your data quality

  • Increase confidence by higher statistical power
  • Find subtle differences between groups
  • See patterns in the data you missed before

Expand your data readout

  • Use over 230 predefined sums and ratios 
  • Create your own metabolism indicators and include them in your analysis
  • Unravel relations between metabolite concentrations

Advance pathway interpretation

  •  Access underlying enzyme activities
  •  Study relevant pathways instead of metabolites

Let your data tell the story

  • Established institutional knowledge
  • Access scientific references in one click
  • Supports biomedical interpretation

For more information on sample preparation, read our guideline on preparation of blood samples for targeted metabolomics.

 

For Research Use Only. Not for use in diagnostic procedures.