Our metabolite of the month DCA is a secondary bile acid product. Interest in DCA was revived in the 1940s, when it was identified as a precursor for the synthesis of corticosteroids
Metabolite of the month – Deoxycholic acid
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Gastroenterology
Gastroenterology is the branch of medicine that deals with the digestive system or gastro-intestinal tract (GIT) and its disorders. The GIT includes the esophagus, stomach, small intestine, large intestine, and rectum, as well as the liver, gallbladder, and pancreas.
Metabolite of the month – Aminobutyric acids
Alpha-, beta- and gamma-aminobutyric acids (AABA, BABA and GABA) are a group of structurally similar nonproteinogenic amino acids.
Metabolite of the month – Histamine
Histamine stimulates smooth muscle contraction, vasodilation, and gastric acid secretion, and plays a role in cell differentiation, proliferation and regeneration
Metabolite of the month – Tryptophan
Tryptophan is a pivotal metabolite in nutrition, inflammation and the gut-brain-axis. This is an overview of what is known about this amino acid although much is left..
Irritable bowel syndrome linked to distinct metabolic profile
A metabolic pattern of patients with irritable bowel syndrome (IBS) was identified, providing the key to non-invasive IBS diagnostics.
Mechanism of gallstone formation
Chromatin mesh of specific immune cells aggregates bile crystals to gallstones and might constitute a promising pharmacological target against gallstone formation.
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