biocrates blog
Applications of metabolomics
Nicotinic acid – From vitamin B3 to precision metabolism
Nicotinic acid has evolved from a pellagra-curing vitamin to a context‑dependent metabolic modulator, linking vitamin B₃ biology with NAD⁺ metabolism, lipid regulation, immunity, and host–microbiome interactions. Its history and mechanisms exemplify how nutritional discoveries have shaped modern precision approaches to cardiometabolic and inflammatory disease.
Exposomics and Metabolomics | The dynamic duo of the post-genomic era
Read in this article about how exposomics and metabolomics together provide a powerful, complementary framework for advancing 5P medicine by linking environmental exposures with measurable metabolic phenotypes.
Eicosapentaenoic acid (EPA) – Anti-inflammatory lipid mediator
Eicosapentaenoic acid (EPA) is an omega‑3 polyunsaturated fatty acid that acts as a precursor to specialized pro‑resolving mediators, including resolvins, which actively dampen inflammatory responses.
Immunotherapy response | Metabolomics accelerating 5P medicine
Metabolomics as an accelerator of 5P medicine |
Part 1: Polyamine acetylation as a driver of immunotherapy response
Biognosys Group at AZ Metabolomics & T32 Symposium
This year’s Arizona Metabolomics & T32 Symposium was hosted by Dr. Haiwei Gu and Dr. Corrie Whisner at Arizona State University in Phoenix, AZ. This one-day event highlighted a variety of emerging research topics and applications in the field of metabolomics, systems biology, and health.
Dimethylglycine – from cold war hype to hot topic
Dimethylglycine is a molecular entry point into individualized, systems-oriented healthcare. Altered DMG levels have been linked to cardiometabolic risk and conditions such as myocardial infarction, diabetes, and metabolic dysfunction-associated liver disease.
Fructose – sweet molecule with systemic impact
Fructose is a simple sugar found in fruits and honey, but also added to many processed foods. Unlike glucose, it is mainly metabolized in the liver, and excessive intake can contribute to metabolic and inflammatory health issues.
How metabolomics is improving healthcare – 6 must-read studies from 2025
biocrates’ standardized metabolomics empowers global research. Here is a selection of how our community of users has translated molecular fingerprints into insights for 5P medicine in 2025.
2025 at biocrates – A year shaped by 5P medicine
2025 was a year shaped by 5P medicine for biocrates. From the evolution of our scientific content to new product highlights and our integration into the Biognosys Group, this year demonstrated how metabolomics brings the five pillars of modern medicine – preventive, predictive, precision, population-based, and participatory – to life.
Homovanillic acid – a major dopamine metabolite
Homovanillic acid (HVA) is a monocarboxylic acid best known for its role as a major dopamine metabolite.