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Microbiome

The microbiome is made of microorganisms living in and on our body. Through metabolism, the microbiome contributes essential metabolites that contribute to our health, but can also release toxic metabolites that contribute to disease. The study of the microbiome together with host biology is currently one of the hottest topics in biomedical research.

Nicotinic acid – From vitamin B3 to precision metabolism

Nicotinic acid – From vitamin B3 to precision metabolism

Nicotinic acid has evolved from a pellagra-curing vitamin to a context‑dependent metabolic modulator, linking vitamin B₃ biology with NAD⁺ metabolism, lipid regulation, immunity, and host–microbiome interactions. Its history and mechanisms exemplify how nutritional discoveries have shaped modern precision approaches to cardiometabolic and inflammatory disease.

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Dimethylglycine – from cold war hype to hot topic

Dimethylglycine – from cold war hype to hot topic

Dimethylglycine is a molecular entry point into individualized, systems-oriented healthcare. Altered DMG levels have been linked to cardiometabolic risk and conditions such as myocardial infarction, diabetes, and metabolic dysfunction-associated liver disease.

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Fructose – sweet molecule with systemic impact

Fructose – sweet molecule with systemic impact

Fructose is a simple sugar found in fruits and honey, but also added to many processed foods. Unlike glucose, it is mainly metabolized in the liver, and excessive intake can contribute to metabolic and inflammatory health issues.

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