Plasma metabolome and microbiota profiles from the SHIP cohort link microbiome instability to liver steatosis, diabetes mellitus, and pancreatic dysfunction
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The metabolite of this month is cholic acid, of the the bile acid class. Notorious for their role in digestion, they are also powerful regulators of metabolism.
The maturation of the newborn´s microbiome is critically dependent on bile acids from liver and can be manipulated by administration of bile acids in mice.
Higher serum bile acid levels and an altered gut microbiome contribute to fibrogenesis, liver injury, and tumorigenesis in cirrhotic and noncirrhotic NASH-HCC.
Metabolomics and 16S rRNA profiling uncover the crosstalk between gut microbiota and statins efficacy that can hide behind inter-individual variability.
biocrates enables reproducible quantitative metabolomics in fecal samples. Understand the challenges associated with this matrix.
“Metabolomics – between Nutrition, Microbiome, and Disease” demonstrates that metabolomics is a powerful tool to study host-microbiota-diet interactions
Metagenomics, metaproteomics and metabolomics create an exciting mix of approaches to understand systematic changes in an organism after external perturbations.
How can the use of antibiotics in animal farming be reduced? Probiotics might be a solution.
Targeted metabolomics support the study of animal health. The diet of cows (high vs low energy) has influence on the metabolite levels of the offspring.
Due to the fact that in Alzheimers bile acids as well as the microbiome play a key role, standardized metabolomics is particularly well adapted to study Alzheimers.
The study of the microbiome is a vital part of personalized medicine. Targeted metabolomics supports patient stratification in Clostridiodes patients.