Trimethylamine oxide (TMAO), which has been suggested to be a “bad” metabolite
Metabolite of the month – Trimethylamine N-oxide (TMAO)
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Microbiome
The microbiome is made of microorganisms living in and on our body. Through metabolism, the microbiome contributes essential metabolites that contribute to our health, but can also release toxic metabolites that contribute to disease. The study of the microbiome together with host biology is currently one of the hottest topics in biomedical research.
3-indoleacetic acid (3-IAA) – Metabolite of the month
The metabolite of this month is 3-IAA, known as the most common plant growth hormone.
p-cresol sulfate – Metabolite of the month
The metabolite of this month is p-cresol sulfate, a sulfate conjugate of the bacterial metabolite p-cresol, which is a uremic toxin.
Melatonin – Metabolite of the month
Our metabolite of the month melatonin is an ancient molecule found in all living organisms from bacteria to humans, with an evolution that can be traced back 2.5 billion years.
Treatment of non-alcoholic fatty liver disease (NAFLD) as a chemopreventive strategy for other chronic disease: a metabolomics perspective
NAFLD is a key player in other chronic diseases – both as a prevalent comorbidity and a contributing factor. Does this mean that treating NAFLD could prevent those conditions?
Metabolite of the month – Deoxycholic acid
Our metabolite of the month DCA is a secondary bile acid product. Interest in DCA was revived in the 1940s, when it was identified as a precursor for the synthesis of corticosteroids
Metabolite of the month – Histamine
Histamine stimulates smooth muscle contraction, vasodilation, and gastric acid secretion, and plays a role in cell differentiation, proliferation and regeneration
Metabolite of the month – Tryptophan
Tryptophan is a pivotal metabolite in nutrition, inflammation and the gut-brain-axis. This is an overview of what is known about this amino acid although much is left..
Metabolite of the month – Indole
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at indole, a product of tryptophan..
Are effects of antibiotics reflected in the metabolome?
Antibiotics influence the gut microbiome and the plasma or fecal metabolome depending on the class of antibiotics and the gut bacterial composition.
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