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Cardiometabolic disease is a major public health concern although it is partly preventable and manageable with appropriate lifestyle changes. The term cardiometabolic disease refers to two groups of diseases with common risk factors: cardiovascular diseases such as stroke and heart attack and metabolic disorders such metabolic syndrome and type 2 diabetes.
Nicotinic acid has evolved from a pellagra-curing vitamin to a context‑dependent metabolic modulator, linking vitamin B₃ biology with NAD⁺ metabolism, lipid regulation, immunity, and host–microbiome interactions. Its history and mechanisms exemplify how nutritional discoveries have shaped modern precision approaches to cardiometabolic and inflammatory disease.
Learn about methionine, a vital sulfur-containing amino acid essential for protein synthesis, metabolism, antioxidant defense, and cellular health. Discover its dietary sources, impact on health, and role in diverse biological processes
Explore the role of indoxyl sulfate, a gut-derived uremic toxin linked to kidney, cardiovascular, and neurological health. Learn about its biosynthesis, impact on chronic disease, and potential as a therapeutic target.
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at kynurenic acid, an important neuroactive metabolite synthesized from tryptophan in the human body.
Metabolomics highlights the significant role of microbial communities in human health, driving a paradigm shift towards towards personalized, proactive healthcare.