biocrates blog
Applications of metabolomics
Make sure your drug fits to your cancer
The response of cancer cells to checkpoint inhibition therapy can be predicted using metabolomics.
Arginine metabolism: Targeted metabolomics and biochemical pathways
Metabolic syndrome is associated with changes in amino acid metabolites. The korean genome and epidemiology study finds involvement of arginase activity
Feature: MetaboINDICATOR and biogenic amines
Targeted metabolomics support the study of animal health. The diet of cows (high vs low energy) has influence on the metabolite levels of the offspring.
Gender differences in brain – revealed by metabolomics
Female and male mice may think differently. Targeted metabolomics reveals differences in brain chemistry between the two which might account for behavioral differences.
A metabolic profile of all-cause mortality risk
To predicting life expectancy standardized and reproducible scientific methods are needed. Metabolomics is one way to approach this question.
Betaine for a healthy life and brain?
Betaine supplementation has a profound effect on phospholipid metabolism. Its effect on brain and liver health can be studied using targeted metabolomics.
Serine – nonessential for you, but essential for cancer
One of the widely accepted hallmarks of cancer is metabolic deregulation. By integrating transcriptome, proteome, and metabolome analysis insights on cancer can be gained.
Microbiome and cognition in Alzheimer´s disease
Due to the fact that in Alzheimers bile acids as well as the microbiome play a key role, standardized metabolomics is particularly well adapted to study Alzheimers.
Metabolomics can indicate favorable response to microbiota transfer
The study of the microbiome is a vital part of personalized medicine. Targeted metabolomics supports patient stratification in Clostridiodes patients.
Metabolomics of acute heart failure
Acute and chronic heart failure can be studied using metabolomics. The metabolic phenotype (especially lipids/ amino acids) rapidly changes upon these condition