biocrates blog
Applications of metabolomics
Metabolism of fatty liver disease and the impact of therapy
New study demonstrates the power of metabolomics in boosting our understanding of fatty liver disease – and possible treatments. Obeticholic acid reverses metabolic changes in NASH.
Lipid biomarkers improve diagnosis of bacterial meningitis
Free phosphatidylcholines in cerebrospinal fluid are highly promising biomarkers for an improved differential diagnosis of bacterial meningitis.
Metabolomics can help identify root causes of hypertension
Targeted metabolomics discriminates between primary and endocrine hypertension.
New analytical method for the quantification of acylcarnitines
Acylcarnitine profiles of melanoma xenografts in mice could be a step towards a new treatment.
Multi-omics reveals new insights into chronic malarias
Host-parasite interactions in chronic and acute malaria were characterized by metabolomics and transcriptomics in macaques and humans.
Elevated liver fat content disrupts the liver-α cell axis
Elevated liver fat is related to hyperglucagonaemia, which reflects the disruption of the liver-α cell axis.
Taurine – Regulator of cellular function
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at Taurine, the most abundant intracellular amino acid in the human body.
Defining the biochemistry of obesity
Increasing degree of metabolic dysregulation visible in the blood metabolome depending on the degree of obesity.
How bile salt hydrolases affect the gut microbiome
Bile acid composition and a complex network of bile salt hydrolases in the gut shape microbial colonization.
Metabolite of the month – Dopamine
Metabolite of the month is your sneak peek into the world of metabolomics. This month discover dopamine, a link between memory, blood pressure, and music.