biocrates blog
Applications of metabolomics
Metabolite of the month – Glycine
Glycine plays a role in metabolic regulation, neurological function, anti-oxidative reactions and protein synthesis. It offers multiple health benefits that may help to treat diabetes, cardiovascular disease, cancer, inflammation and obesity.
Short- and medium-chain fatty acids
During this webinar you can learn how microbiota impact the gut-immune axis through short- and medium-chain fatty acids
A metabolomics perspective on major depressive disorder
Depression has an impact on nitric oxide synthesis, urea cycle, inflammation, and ADMA levels. Metabolomics is a means to study depressive disorders and gives insights on disease etiology
Advancing cancer treatment by targeting dysregulated metabolism – A roadmap
Cancer cells adjust metabolic program to their specific energy needs in response to challenging microenvironment, which frequently results in cancer cell “addiction” to certain metabolic pathways. Those “addictions” could be deployed as treatment targets. Metabolic profiling by providing quantitative measure of metabolic processes offers attractive strategy for investigation of not only cancer cells “addictions” but also metabolic switches contributing to treatment resistance.
Targeted metabolomics in neurodegenerative diseases
You can learn how metabolomics can be applied to research in neurodegenerative diseases in a quantitative and reproducible manner.
3 assets needed to excel at metabolomics data interpretation
Ornithine – Metabolite of the month
Our metabolite of the month is Ornithine, a non-essential, non-proteinogenic amino acid that plays an essential role in the urea cycle.
Phosphatidylethanolamines – Key lipids in cellular function and membrane integrity
Phosphatidylethanolamine (PE) is a sub-class of phospholipids with a variety of functions in animals, plants and microorganisms. Like other phospholipids, PEs are more than simply the building blocks of membranes
Metabolite – 3-Hydroxy Glutaric Acid (A biomarker for a rare disease)
3-hydroxyglutaric acid is a little known metabolite with great application for the diagnosis of a rare disease.
ICYMI – Recap from “Pan-cohort studies – the future of population health” symposium
With more than 20 hours of cutting-edge science in the rearview mirror, it’s time to reflect on our recent “Pan-cohort studies – The future of population health” event.