Homovanillic acid (HVA) is a monocarboxylic acid best known for its role as a major dopamine metabolite.
Homovanillic acid – a major dopamine metabolite
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Louise
Bilirubin – from waste pigment to regulatory metabolite
Bilirubin reduces oxidative stress, supports liver and cardiovascular functions, and protects against inflammation-related health conditions.
Itaconic acid – from immune defense to a target in chronic disease
Itaconic acid shapes immune responses, affects the gut microbiome, and may influence cardiovascular, neurological, metabolic, and cancer outcomes.
N-acetyl-aspartic acid (NAA) – Significant metabolite for brain function, metabolism, and disease
N-acetyl-aspartic acid (NAA) is a key brain metabolite involved in neuronal health, myelin synthesis, and metabolism. Its strong MRS signal makes it a valuable biomarker for neurological disorders, while emerging research links it to oncology, psychiatric conditions, and the gut-brain axis. As metabolomics advances, NAA’s role in diagnostics and personalized medicine continues to expand.
Citric acid – Key metabolite in energy production, bone health, and disease therapy
A key metabolite in cellular energy production and various physiological processes such as fatty acid metabolism, amino acid synthesis, calcium signaling, anticoagulation and the regulation of pH balance.
Oxaloacetic acid (OAA) – Key metabolite in metabolism, disease, and therapeutic innovation
A key metabolite in the citric acid cycle, essential for energy production and metabolic processes
Methionine – a crucial amino acid in metabolism, antioxidant defense, and cellular function
Learn about methionine, a vital sulfur-containing amino acid essential for protein synthesis, metabolism, antioxidant defense, and cellular health. Discover its dietary sources, impact on health, and role in diverse biological processes
Indoxyl sulfate – Metabolite of the month
Explore the role of indoxyl sulfate, a gut-derived uremic toxin linked to kidney, cardiovascular, and neurological health. Learn about its biosynthesis, impact on chronic disease, and potential as a therapeutic target.
Kynurenic acid – A neuroprotective metabolite with key roles in brain health and immune function
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at kynurenic acid, an important neuroactive metabolite synthesized from tryptophan in the human body.
Butyric acid – A vital short-chain fatty acid for gut health and metabolic wellness
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at butyric acid, which is one of three common SCFAs in the human gut.
Choline – An essential nutrient for brain function, liver health, and beyond
The metabolite of this month is choline, implicated in various aspects of neurological and cardiovascular health and function.
Trimethylamine N-oxide (TMAO) – A crucial metabolite linking diet, gut health, and cardiovascular risk
Trimethylamine oxide (TMAO), which has been suggested to be a “bad” metabolite
3-indoleacetic acid (3-IAA) – Exploring its impact on human health and metabolism
The metabolite of this month is 3-IAA, known as the most common plant growth hormone.
Melatonin – The sleep-regulating hormone with far-reaching health benefits
Our metabolite of the month melatonin is an ancient molecule found in all living organisms from bacteria to humans, with an evolution that can be traced back 2.5 billion years.
Sphingosine-1-phosphate (S1P) – A master regulator in cellular signaling and disease pathways
In our metabolite of the month series, our scientists look at one specific metabolite each month. Topics of discussion include the biosynthesis and degradation in a broader health context, and the effect of dysregulation. In this month´s article, they took a closer look at sphingosine-1-phosphate.
Arginine – Essential amino acid driving nitric oxide production and cardiovascular health
In our metabolite of the month series, our scientists look at one specific metabolite each month. Topics of discussion include the biosynthesis and degradation in a broader health context, and the effect of dysregulation. In this month´s article, they took a closer look at Arginine.
Metabolite of the month – Deoxycholic acid
Our metabolite of the month DCA is a secondary bile acid product. Interest in DCA was revived in the 1940s, when it was identified as a precursor for the synthesis of corticosteroids
Alpha-aminoadipic acid – Metabolite of the month
Aminoadipic acid is an alpha amino acid, meaning its amino group is attached to the carbon atom in the alpha position. It’s a nonproteinogenic amino acid found in all eukaryotes.
Metabolite of the month – Aminobutyric acids
Alpha-, beta- and gamma-aminobutyric acids (AABA, BABA and GABA) are a group of structurally similar nonproteinogenic amino acids.
Histamine – Metabolite of the month
Histamine stimulates smooth muscle contraction, vasodilation, and gastric acid secretion, and plays a role in cell differentiation, proliferation and regeneration
Metabolite of the month – Glycine
Glycine plays a role in metabolic regulation, neurological function, anti-oxidative reactions and protein synthesis. It offers multiple health benefits that may help to treat diabetes, cardiovascular disease, cancer, inflammation and obesity.
Ornithine – Metabolite of the month
Our metabolite of the month is Ornithine, a non-essential, non-proteinogenic amino acid that plays an essential role in the urea cycle.
Lactic acid – Metabolite of the month
Lactic acid is produced by various cells in the body, including muscle cells, red blood cells and neurons
Metabolite of the month – Tryptophan
Tryptophan is a pivotal metabolite in nutrition, inflammation and the gut-brain-axis. This is an overview of what is known about this amino acid although much is left..
Cholesterol – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at cholesterol..
Cortisol – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at cortisol, a steroid hormone involved in stress response and beyond.
Phosphatidylcholines – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at phosphatidylcholines, a class of lipids involved in much more than membrane composition.
Indole – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at indole, a product of tryptophan..
Leucine – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. This month, we look at leucine, an amino acid involved in energy metabolism, autophagy, and more.
Isovaleric acid – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at Isovaleric acid, a five-carbon branched ..
Creatinine – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. This month we took a closer look at creatinine, a non-protein nitrogenous waste product generated during energy breakdown in muscles.
Taurine – Regulator of cellular function
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at Taurine, the most abundant intracellular amino acid in the human body.
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