Speaker | Prof. Dr. Konrad Aden
Affiliation | Universitätsklinikum Schleswig-Holstein, Kiel, Germany
Host-microbial interactions as pathophysiological nexus in inflammatory bowel disease
In inflammatory bowel diseases, many patients do not respond to therapy or do not maintain disease control long-term. Precision medicine-based approaches to overcome the “therapeutic ceiling” are urgently needed. Immunometabolism is an important component to the pathophysiology of inflammatory bowel diseases and thus may serve the purpose of contributing to better and more personalized therapy decisions. While several metabolic pathways contribute, the talk puts special emphasis on the metabolism of the essential amino acid tryptophan.
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