Accumulation of neurotoxic kynurenine metabolites with aging represents the mechanism of neuromuscular defects linking chronic inflammation to physical frailty.
Kynurenine metabolites mediate neuromuscular dysfunction
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Neurology
Kynurenine – Metabolite of the month
Kynurenine is a tryptophan-derived metabolite at the crossroads between neurology, immunology and cancer
Machine learning for ALS progression biomarker discovery
How to combine targeted metabolomics and machine learning algorithms to identify biomarkers associated with ALS disease progression.
Mitochondria’s role in clinical depression
What does brain activity look like after anti-depressant treatment and what is the basis for prescribing serotonin re-uptake inhibitors in the first place?
Is Alzheimer’s a metabolic disease?
Alzheimer’s disease (AD) has many facets. Metabolomics supports Alzheimer’s early diagnosis and research on the treatment of AD.