The metabolite of this month is 3-IAA, known as the most common plant growth hormone.
3-indoleacetic acid (3-IAA) – Exploring its impact on human health and metabolism
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Microbiome
The microbiome is made of microorganisms living in and on our body. Through metabolism, the microbiome contributes essential metabolites that contribute to our health, but can also release toxic metabolites that contribute to disease. The study of the microbiome together with host biology is currently one of the hottest topics in biomedical research.
p-cresol sulfate – A key uremic toxin with implications for gut health and chronic disease
The metabolite of this month is p-cresol sulfate, a sulfate conjugate of the bacterial metabolite p-cresol, which is a uremic toxin.
Melatonin – The sleep-regulating hormone with far-reaching health benefits
Our metabolite of the month melatonin is an ancient molecule found in all living organisms from bacteria to humans, with an evolution that can be traced back 2.5 billion years.
Treatment of non-alcoholic fatty liver disease (NAFLD) as a chemopreventive strategy for other chronic disease: a metabolomics perspective
NAFLD is a key player in other chronic diseases – both as a prevalent comorbidity and a contributing factor. Does this mean that treating NAFLD could prevent those conditions?
Metabolite of the month – Deoxycholic acid
Our metabolite of the month DCA is a secondary bile acid product. Interest in DCA was revived in the 1940s, when it was identified as a precursor for the synthesis of corticosteroids
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