3-hydroxyglutaric acid is a little known metabolite with great application for the diagnosis of a rare disease.
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Metabolites are essential for life. They are the products of the chemical processes that occur in the body and are necessary for the body to function. Metabolites can be used as biomarkers to diagnose disease and to assess treatment efficacy.
In this blog, we’ll take a closer look at one specific metabolite. Topics of discussion include the biosynthesis and degradation in a broader health context, and the effects of dysregulation in disease.
Lactic acid – Metabolite of the month
Lactic acid is produced by various cells in the body, including muscle cells, red blood cells and neurons
NAD+ (nicotinamide adenine dinucleotide) – Metabolite of the month
NAD is best known as a master regulator of redox reactions, but it is also a substrate used by many enzymes to fine tune cell biology.
Metabolite of the month – Tryptophan
Tryptophan is a pivotal metabolite in nutrition, inflammation and the gut-brain-axis. This is an overview of what is known about this amino acid although much is left..
Cholesterol – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at cholesterol..