Metabolite of the month - biocrates life sciences ag

All posts to the category

Metabolite of the month

Metabolites are essential for life. They are the products of the chemical processes that occur in the body and are necessary for the body to function. Metabolites can be used as biomarkers to diagnose disease and to assess treatment efficacy.

In this blog, we’ll take a closer look at one specific metabolite. Topics of discussion include the biosynthesis and degradation in a broader health context, and the effects of dysregulation in disease.

Metabolite of the month – Aminobutyric acids

Alpha-, beta- and gamma-aminobutyric acids (AABA, BABA and GABA) are a group of structurally similar nonproteinogenic amino acids.

Metabolite of the month – Histamine

Histamine stimulates smooth muscle contraction, vasodilation, and gastric acid secretion, and plays a role in cell differentiation, proliferation and regeneration

Metabolite of the month – Glycine

Glycine plays a role in metabolic regulation, neurological function, anti-oxidative reactions and protein synthesis. It offers multiple health benefits that may help to treat diabetes, cardiovascular disease, cancer, inflammation and obesity.

Phosphatidylethanolamines – Key lipids in cellular function and membrane integrity

Phosphatidylethanolamine (PE) is a sub-class of phospholipids with a variety of functions in animals, plants and microorganisms. Like other phospholipids, PEs are more than simply the building blocks of membranes

Metabolite – 3-Hydroxy Glutaric Acid (A biomarker for a rare disease)

3-hydroxyglutaric acid is a little known metabolite with great application for the diagnosis of a rare disease.

Metabolite of the month – Lactic acid

Lactic acid is produced by various cells in the body, including muscle cells, red blood cells and neurons

Metabolite of the month – NAD+ (nicotinamide adenine dinucleotide)

NAD is best known as a master regulator of redox reactions, but it is also a substrate used by many enzymes to fine tune cell biology.

Metabolite of the month – Tryptophan

Tryptophan is a pivotal metabolite in nutrition, inflammation and the gut-brain-axis. This is an overview of what is known about this amino acid although much is left..