Cell culture metabolomics is an excellent tool to decrease drug development costs while increasing speed and success rate. Its applicability has been proven in numerous studies.
Cell culture metabolomics – The shortcut to drug development
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Pharmacology
Adverse effects in immunotherapy
Only 20–30 % of patients experience a long-term benefit from immunotherapy, but the high rate of adverse events in immunotherapies is also a matter of intense research and scientific debate
Therapy resistance: could metabolomic biomarkers remove this major roadblock to successful pharmaceutical research and development programs?
Pharmaceutical therapies have created huge benefits for society in expanding healthy life span
Are effects of antibiotics reflected in the metabolome?
Antibiotics influence the gut microbiome and the plasma or fecal metabolome depending on the class of antibiotics and the gut bacterial composition.
Metabolic effects of anti-TNF α therapy
Anti-TNF α therapy in Crohn´s Disease improves liver steatosis through changes in gut bacteria and triglycerides.
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