N-acetyl-aspartic acid (NAA) is a key brain metabolite involved in neuronal health, myelin synthesis, and metabolism. Its strong MRS signal makes it a valuable biomarker for neurological disorders, while emerging research links it to oncology, psychiatric conditions, and the gut-brain axis. As metabolomics advances, NAA’s role in diagnostics and personalized medicine continues to expand.
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Metabolites are essential for life. They are the products of the chemical processes that occur in the body and are necessary for the body to function. Metabolites can be used as biomarkers to diagnose disease and to assess treatment efficacy.
In this blog, we’ll take a closer look at one specific metabolite. Topics of discussion include the biosynthesis and degradation in a broader health context, and the effects of dysregulation in disease.
Citric acid – Key metabolite in energy production, bone health, and disease therapy
A key metabolite in cellular energy production and various physiological processes such as fatty acid metabolism, amino acid synthesis, calcium signaling, anticoagulation and the regulation of pH balance.
Oxaloacetic acid (OAA) – Key metabolite in metabolism, disease, and therapeutic innovation
A key metabolite in the citric acid cycle, essential for energy production and metabolic processes
Inosine – Metabolite of the month
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at inosine.
Methionine – a crucial amino acid in metabolism, antioxidant defense, and cellular function
Learn about methionine, a vital sulfur-containing amino acid essential for protein synthesis, metabolism, antioxidant defense, and cellular health. Discover its dietary sources, impact on health, and role in diverse biological processes