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Metabolite of the month

Metabolites are essential for life. They are the products of the chemical processes that occur in the body and are necessary for the body to function. Metabolites can be used as biomarkers to diagnose disease and to assess treatment efficacy.

In this blog, we’ll take a closer look at one specific metabolite. Topics of discussion include the biosynthesis and degradation in a broader health context, and the effects of dysregulation in disease.

N-acetyl-aspartic acid (NAA) – Significant metabolite for brain function, metabolism, and disease

N-acetyl-aspartic acid (NAA) – Significant metabolite for brain function, metabolism, and disease

N-acetyl-aspartic acid (NAA) is a key brain metabolite involved in neuronal health, myelin synthesis, and metabolism. Its strong MRS signal makes it a valuable biomarker for neurological disorders, while emerging research links it to oncology, psychiatric conditions, and the gut-brain axis. As metabolomics advances, NAA’s role in diagnostics and personalized medicine continues to expand.

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