biocrates blog
Applications of metabolomics
Taurine – Regulator of cellular function
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at Taurine, the most abundant intracellular amino acid in the human body.
Defining the biochemistry of obesity
Increasing degree of metabolic dysregulation visible in the blood metabolome depending on the degree of obesity.
How bile salt hydrolases affect the gut microbiome
Bile acid composition and a complex network of bile salt hydrolases in the gut shape microbial colonization.
Metabolite of the month – Dopamine
Metabolite of the month is your sneak peek into the world of metabolomics. This month discover dopamine, a link between memory, blood pressure, and music.
Metabolomics reveals link between adipose tissue and severe COVID-19
A lipid signature is associated with disease severity and inflammatory status in patients with COVID-19.
Could metabolites enhance pharmacological cancer treatments?
Metabolites in action: metabolomics reveals link between mitochondrial respiration and proteasomal degradation mechanisms, with important implications for cancer drugs.
Prenatal PFAS exposure leads to liver injuries in children
HELIX metabolomics study links prenatal PFAS (perfluoralkyl substances) exposure to metabolic origin of liver injuries in children.
Mechanism of gallstone formation
Chromatin mesh of specific immune cells aggregates bile crystals to gallstones and might constitute a promising pharmacological target against gallstone formation.
7 tips to make your first metabolomics project successful (with story)
To obtain optimal results from your metabolomics project you might want to answer these seven questions to increase your success.
Modulating gut microbiota with prebiotics could control type 2 diabetes
Modulation of gut microbiota with prebiotic Fructooligosaccharides (FOS) led to discovery of two novel enterosynes (12-HETE and enkephalin), with potential to control type 2 diabetes