biocrates blog
Applications of metabolomics
New analytical method for the quantification of acylcarnitines
Acylcarnitine profiles of melanoma xenografts in mice could be a step towards a new treatment.
Multi-omics reveals new insights into chronic malarias
Host-parasite interactions in chronic and acute malaria were characterized by metabolomics and transcriptomics in macaques and humans.
Elevated liver fat content disrupts the liver-α cell axis
Elevated liver fat is related to hyperglucagonaemia, which reflects the disruption of the liver-α cell axis.
Taurine – Regulator of cellular function
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at Taurine, the most abundant intracellular amino acid in the human body.
Defining the biochemistry of obesity
Increasing degree of metabolic dysregulation visible in the blood metabolome depending on the degree of obesity.
How bile salt hydrolases affect the gut microbiome
Bile acid composition and a complex network of bile salt hydrolases in the gut shape microbial colonization.
Metabolite of the month – Dopamine
Metabolite of the month is your sneak peek into the world of metabolomics. This month discover dopamine, a link between memory, blood pressure, and music.
Metabolomics reveals link between adipose tissue and severe COVID-19
A lipid signature is associated with disease severity and inflammatory status in patients with COVID-19.
Could metabolites enhance pharmacological cancer treatments?
Metabolites in action: metabolomics reveals link between mitochondrial respiration and proteasomal degradation mechanisms, with important implications for cancer drugs.
Prenatal PFAS exposure leads to liver injuries in children
HELIX metabolomics study links prenatal PFAS (perfluoralkyl substances) exposure to metabolic origin of liver injuries in children.