biocrates blog
Applications of metabolomics
Immunotherapy response | Metabolomics accelerating 5P medicine
Metabolomics as an accelerator of 5P medicine |
Part 1: Polyamine acetylation as a driver of immunotherapy response
Biognosys Group at AZ Metabolomics & T32 Symposium
This year’s Arizona Metabolomics & T32 Symposium was hosted by Dr. Haiwei Gu and Dr. Corrie Whisner at Arizona State University in Phoenix, AZ. This one-day event highlighted a variety of emerging research topics and applications in the field of metabolomics, systems biology, and health.
Dimethylglycine – from cold war hype to hot topic
Dimethylglycine is a molecular entry point into individualized, systems-oriented healthcare. Altered DMG levels have been linked to cardiometabolic risk and conditions such as myocardial infarction, diabetes, and metabolic dysfunction-associated liver disease.
Fructose – sweet molecule with systemic impact
Fructose is a simple sugar found in fruits and honey, but also added to many processed foods. Unlike glucose, it is mainly metabolized in the liver, and excessive intake can contribute to metabolic and inflammatory health issues.
How metabolomics is improving healthcare – 6 must-read studies from 2025
biocrates’ standardized metabolomics empowers global research. Here is a selection of how our community of users has translated molecular fingerprints into insights for 5P medicine in 2025.
2025 at biocrates – A year shaped by 5P medicine
2025 was a year shaped by 5P medicine for biocrates. From the evolution of our scientific content to new product highlights and our integration into the Biognosys Group, this year demonstrated how metabolomics brings the five pillars of modern medicine – preventive, predictive, precision, population-based, and participatory – to life.
Homovanillic acid – a major dopamine metabolite
Homovanillic acid (HVA) is a monocarboxylic acid best known for its role as a major dopamine metabolite.
p-cresol glucuronide – detoxicant or uremic toxin?
p-cresol glucuronide (pCG) is a liver-derived conjugate of the gut microbial metabolite p-cresol, excreted via the kidneys, and it reflects gut-microbiome activity in blood and urine.
Peroxisome biogenesis disorders and the lipidome
Explore how disruptions in peroxisomal lipid metabolism drive disease phenotypes and how lipidomics can reveal early biomarkers of rare disorders.
cAMP – a currency of cell signaling
Cyclic adenosine monophosphate (cAMP) is a universal second messenger which translates extracellular cues into cellular responses regulating metabolism, gene expression, neurobiology, and immunity. Dysregulated cAMP signaling contributes to cancer, inflammation, and neurological disorders, making it a key target in precision medicine.