Itaconic acid shapes immune responses, affects the gut microbiome, and may influence cardiovascular, neurological, metabolic, and cancer outcomes.
Itaconic acid – from immune defense to a target in chronic disease
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Neurology
Methylmalonic acid – key marker of vitamin B12 status and metabolism
Methylmalonic acid (MMA) is a key biomarker of vitamin B12 deficiency and plays a central role in energy metabolism.
Spermidine – Unlocking the secrets of cellular aging and longevity
The metabolite of this month is spermidine, a biogenic amine with applications in cancer, neurology and hair research.
Propionic acid – A short-chain fatty acid with big impact
A short-chain fatty acid produced by gut, it plays a role in energy metabolism, immune regulation, and neurological health
N-acetyl-aspartic acid (NAA) – Significant metabolite for brain function, metabolism, and disease
N-acetyl-aspartic acid (NAA) is a key brain metabolite involved in neuronal health, myelin synthesis, and metabolism. Its strong MRS signal makes it a valuable biomarker for neurological disorders, while emerging research links it to oncology, psychiatric conditions, and the gut-brain axis. As metabolomics advances, NAA’s role in diagnostics and personalized medicine continues to expand.