Explore the role of indoxyl sulfate, a gut-derived uremic toxin linked to kidney, cardiovascular, and neurological health. Learn about its biosynthesis, impact on chronic disease, and potential as a therapeutic target.
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Kynurenic acid – A neuroprotective metabolite with key roles in brain health and immune function
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at kynurenic acid, an important neuroactive metabolite synthesized from tryptophan in the human body.
Butyric acid – A vital short-chain fatty acid for gut health and metabolic wellness
Metabolite of the month is your sneak peek into the world of metabolomics. In this month´s article, we took a closer look at butyric acid, which is one of three common SCFAs in the human gut.
Melatonin – The sleep-regulating hormone with far-reaching health benefits
Our metabolite of the month melatonin is an ancient molecule found in all living organisms from bacteria to humans, with an evolution that can be traced back 2.5 billion years.
Sphingosine-1-phosphate (S1P) – A master regulator in cellular signaling and disease pathways
In our metabolite of the month series, our scientists look at one specific metabolite each month. Topics of discussion include the biosynthesis and degradation in a broader health context, and the effect of dysregulation. In this month´s article, they took a closer look at sphingosine-1-phosphate.