Bilirubin reduces oxidative stress, supports liver and cardiovascular functions, and protects against inflammation-related health conditions.
Bilirubin – from waste pigment to regulatory metabolite
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Microbiome
The microbiome is made of microorganisms living in and on our body. Through metabolism, the microbiome contributes essential metabolites that contribute to our health, but can also release toxic metabolites that contribute to disease. The study of the microbiome together with host biology is currently one of the hottest topics in biomedical research.
Itaconic acid – from immune defense to a target in chronic disease
Itaconic acid shapes immune responses, affects the gut microbiome, and may influence cardiovascular, neurological, metabolic, and cancer outcomes.
Participatory medicine – Transform medicine with metabolomics – part 5 of 5
In this five-part blog series, Alice Limonciel explores the role of metabolomics in 5P medicine. In this final article of our 5P medicine series, we explore how metabolomics empowers participatory medicine by enabling patients to collect meaningful health data from home. Learn how at-home microsampling devices expand access to testing, why analyte stability and reference ranges are critical for reliable interpretation, and how these tools can bring omics-driven healthcare to remote and underserved populations.
Methylmalonic acid – key marker of vitamin B12 status and metabolism
Methylmalonic acid (MMA) is a key biomarker of vitamin B12 deficiency and plays a central role in energy metabolism.
UDCA – reducing inflammation and supporting bile flow
The metabolite of this month is UDCA, a secondary bile acid metabolite which plays a significant role in hepatology, neurology, and gastrointestinal research.