Itaconic acid shapes immune responses, affects the gut microbiome, and may influence cardiovascular, neurological, metabolic, and cancer outcomes.
Itaconic acid – from immune defense to a target in chronic disease
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Metabolite of the month
Metabolites are essential for life. They are the products of the chemical processes that occur in the body and are necessary for the body to function. Metabolites can be used as biomarkers to diagnose disease and to assess treatment efficacy.
In this blog, we’ll take a closer look at one specific metabolite. Topics of discussion include the biosynthesis and degradation in a broader health context, and the effects of dysregulation in disease.
Methylmalonic acid – key marker of vitamin B12 status and metabolism
Methylmalonic acid (MMA) is a key biomarker of vitamin B12 deficiency and plays a central role in energy metabolism.
UDCA – reducing inflammation and supporting bile flow
The metabolite of this month is UDCA, a secondary bile acid metabolite which plays a significant role in hepatology, neurology, and gastrointestinal research.
Spermidine – Unlocking the secrets of cellular aging and longevity
The metabolite of this month is spermidine, a biogenic amine with applications in cancer, neurology and hair research.
Propionic acid – A short-chain fatty acid with big impact
A short-chain fatty acid produced by gut, it plays a role in energy metabolism, immune regulation, and neurological health