2025 was a year shaped by 5P medicine for biocrates. From the evolution of our scientific content to new product highlights and our integration into the Biognosys Group, this year demonstrated how metabolomics brings the five pillars of modern medicine – preventive, predictive, precision, population-based, and participatory – to life.
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Homovanillic acid – a major dopamine metabolite
Homovanillic acid (HVA) is a monocarboxylic acid best known for its role as a major dopamine metabolite.
p-cresol glucuronide – detoxicant or uremic toxin?
p-cresol glucuronide (pCG) is a liver-derived conjugate of the gut microbial metabolite p-cresol, excreted via the kidneys, and it reflects gut-microbiome activity in blood and urine.
Peroxisome biogenesis disorders and the lipidome
Explore how disruptions in peroxisomal lipid metabolism drive disease phenotypes and how lipidomics can reveal early biomarkers of rare disorders.
cAMP – a currency of cell signaling
Cyclic adenosine monophosphate (cAMP) is a universal second messenger which translates extracellular cues into cellular responses regulating metabolism, gene expression, neurobiology, and immunity. Dysregulated cAMP signaling contributes to cancer, inflammation, and neurological disorders, making it a key target in precision medicine.





