Short-chain fatty acid PLUS (SCFA+) assay
Short-chain fatty acid PLUS assay
With the biocrates SCFA+ assay, standardized and quantitative study of diet, microbiome and health becomes accessible.
Explore the broadest coverage of short- and medium-chain fatty acids to gain a comprehensive view on microbial activity and energy metabolism.
Short-chain fatty acids (SCFAs) and medium-chain fatty acids (MCFAs) are important energy-supplying metabolites. They are also signaling molecules involved in the regulation of carbohydrate and lipid metabolism, as well as mediators of the gut microbiome-immune axis and the gut-brain axis. Aberrations in the metabolism of SCFAs and MCFAs can result in a wide range of disorders including diabetes, neurodegenerative diseases, and cancer. The combined analysis of SCFAs and MCFAs can provide crucial insights into the diet-microbiome-host interaction, energy homeostasis, and health status.
Comprehensive coverage
- Highest coverage of short-, branched-, and medium-chain fatty acids in a single assay
- Quantitative assay to enable calculation of relevant metabolite sums and ratios
Clinical applications
- The role of diet in inflammation, energy metabolism, insulin resistance/T2D, autoimmune diseases
- The link to gut microbiota metabolism and gut-brain axis as well as gut-immune axis
Reliable and reproducible
- Results can be combined with other biocrates kit or assay results for maximal insights
- Data is absolute and quantitative enabling biomarkers and therapeutic target studies
Understand the implications
- Support in data interpretation possible
- Tools to translate metabolomics into knowledge
Look at 19 short- and medium-chain fatty acids included in this assay
- Acetic acid (FA 2:0)
- Propionic acid (FA 3:0)
- Isobutyric acid (FA 3:0-2M)
- Butyric acid (FA 4:0)
- 2-Methylbutyric acid (FA 4:0-2M)
- Isovaleric acid (FA 4:0-3M)
- Valeric acid (FA 5:0) 2-Methylvaleric acid (FA 5:0-2M)
- 3-Methylvaleric acid (FA 5:0-3M)
- Isocaproic acid (FA 5:0-4M)
- Caproic acid (FA 6:0)
- 4-Methylhexanoic acid (FA 6:0-4M)
- 5-Methylhexanoic acid (FA 6:0-5M)
- Heptanoic acid (FA 7:0)
- Caprylic acid (FA 8:0)
- Nonanoic acid (FA 9:0)
- Capric acid (FA 10:0)
- Undecanoic acid (FA 11:0)
- Lauric acid (FA 12:0)
Barbara Ustaszewski, PhD
Scientist | Research & Development
biocrates life sciences, Innsbruck, Austria
This virtual event discusses
- how microbiota impact the gut-immune axis through short- and medium-chain fatty acids
- how short- and medium-chain fatty acids act as signaling molecules for a healthy metabolism
- how you can study the effects of short- and medium-chain fatty acids and gain insights into the cross-talk between diet, microbiota, and energy metabolism
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Learn more
Short-chain fatty acid PLUS assay
The ideal triad for studying metabolic health and the microbiome
Short-chain fatty acids (SCFAs)
Microbial metabolites involved in metabolic health, energy metabolism, and immune balance
Branched-chain fatty acids (BCFAs)
Diet-based gut bacterial mediators of the gut-brain axis
Medium-chain fatty acids (MCFAs)
Energy carriers involved in insulin resistance and the gut-immune axis
SCFAs are important tissue-specific energy and signaling molecules
Besides an energy source, MCFAs exert tissue-specific metabolic regulatory functions
Sample requirements (Application note)
- 60 μl plasma | serum
- 200-500 mg feces (wet weight); minimum technical amount 50 mg
- 3-spot sampling (recommended)
- Need a different sample matrix? Please contact us.