Metabolic phenotyping services

Metabolic phenotyping services

Metabolomics is the omics technology dealing with the detection, identification, and quantification of metabolites. The obtained results most closely reflect the phenotype of a biological system and are therefore increasingly acknowledged in research.

Expert support from study design to actionable results

Our metabolic phenotyping services enable a quality-controlled, highly reproducible, quantitative analysis across the metabolic spectrum. The expert services offer full support in every step of your project, including sampling and sample shipment, project management, statistical analysis, and biomedical data interpretation.

Comprehensive analytical portfolio

Best fit for every research question
Quality-controlled analysis in ISO certified laboratory
Customized assay development

Project management

Expert support from study design to actionable results
Turn-around time is typically 12 weeks after sample receipt
Recommendations for sample preparation, storage, and shipment

Data analysis and biostatistics

Expert analysis of targeted metabolomics data
Profound expertise in biostatistics
Identification of key results

Interpretation and pathway analysis

Established institutional knowledge at your service
State-of-the-art interpretation of results
Metabolic pathway visualizations

Comprehensive analytical portfolio

Our metabolomic phenotyping services cover a wide range of physiological processes and metabolic pathways that can be customized to best fit any metabolomics project. Choose from 8 targeted quantitative assays covering over 1,000 metabolites of relevance to humans as well as a variety of other species, in vitro experiments, and most biological matrices.

Approach	Assay name	Number & Class of metabolites
Quantitative profiling assays	MxP® Quant 500 XL kit	Up to 107 small molecules & 912 lipids
	MxP® Quant 500 kit	Up to 107 small molecules & 523 lipids
	AbsoluteIDQ® p180 kit	Up to 43 small molecules & 145 lipids
Specialized quantitative assays	AbsoluteIDQ® Stero17 kit	Up to 17 steroid hormones
	AbsoluteIDQ® Bile Acids kit	Up to 20 bile acids
	Eicosanoid assay	Up to 17 eicosanoids
	Fatty acid assay (total / free)	Up to 31 / 32 fatty acids
	Oxysterol assay	Up to 18 free (oxy-) sterols
	Short-chain fatty acid PLUS assay	Up to 19 Short-, medium-, and branched-chain fatty acids
	Tryptophan metabolism assay	Up to 17 metabolites from the tryptophan pathway
	Acylcarnitine assay	Up to 43 acylcarnitines + free carnitine

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Technical considerations

Sample preparation methods can strongly influence the extraction yield of metabolites and the overall sensitivity of metabolomics experiments. Our scientists are experienced in handling and preparing samples from a broad range of biological matrices from various species.

Below is a non-exhaustive list of the species/matrices processed over the years. To check on the current recommendations for a particular species or matrix of interest, please contact us.

Species

Human
Laboratory animals (mouse, rat, dog, primates, hamster, guinea pig, fish, C. elegans…)
Farm animals (cow, pig, chicken, sheep, goat, fish…)
Bioprocessing: yeast cultures, CHO cells, medium and supplements

Matrices

Bodily fluids: plasma, serum, whole blood, urine, interstitial fluid, saliva, cerebrospinal fluid, milk, bronchioalveolar lavage fluid (BALF)…
Tissues: liver, kidney, brain, lung, prostate, ovary, breast, colon, pancreas, muscle, skin
Cell culture: lysates from cultivated cell lines and primary cells, supernatant medium
Others: feces, fecal content, dried blood spots (DBS), dried plasma spots

Data analysis & Statistics

Interpretations & pathway analysis

Laboratories offering kit measurement