MxP® Quant 1000 kit

Transform medicine with metabolomics

MxP® Quant 1000 kit

The new standard of excellence in quantitative metabolomics

Transform medicine with metabolomics

MxP® Quant 1000 delivers groundbreaking coverage of biomarkers in a single kit, setting a new standard of excellence for in quantitative metabolomics profiling. High analytical precision is achieved from minimal sample volume, delivering deep biological insights for fundamental, pharmaceutical and clinical research. MxP® Quant 1000 empowers scientists to decipher chronic disease mechanisms and detect phenotypic changes, contributing to the development of innovative therapeutic solutions that will lead the transformation of medicine.

The new standard of excellence in quantitative metabolomics

MxP® Quant 1000 delivers groundbreaking coverage of biomarkers in a single kit, setting a new standard of excellence for in quantitative metabolomics profiling. High analytical precision is achieved from minimal sample volume, delivering deep biological insights for fundamental, pharmaceutical and clinical research. MxP® Quant 1000 empowers scientists to decipher chronic disease mechanisms and detect phenotypic changes, contributing to the development of innovative therapeutic solutions that will lead the transformation of medicine.

Unique pathway coverage

100s of pathways from core metabolism and microbiome-host interactions
Quantification of up to 1,881 biomarkers from only 40 µL of sample

Decipher chronic disease

Broadest small molecules and lipids panel to address chronic disease, cancer, and aging
Instant insights from 648 sums and ratios based on scientific literature

Ready-to-use

Complete solution with integrated end-to-end workflow
Validated methods for key mass spectrometry platforms

Quantitative & standardized

High analytical precision from hundreds of calibrators and internal standards
Rapid metabolite quantification by AI-driven automated peak picking

Kit components

Patented 96-well plate configuration
Stable isotope-labeled internal standards
Calibration standards, quality controls, and system suitability test mixes

Methods and protocols

Validated, instrument-specific methods
Quick-start guide and user manual
Protocols for different matrices

WebIDQ workflow manager

Cloud-based workflow solution (different subscription plans available)
Project design, quantification, and statistical analysis in a single platform
Integrated MetaboINDICATOR tool for automated calculation of sums and ratios

LC-MS platforms

Triple quadrupole mass spectrometers from Agilent, SCIEX, and Waters
Standard flow UHPLC system
Column and precolumn (available separately from biocrates)

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Quantitative analysis of up to 1,233 metabolites from 49 biochemical classes

Small molecule panel

Alkaloids (2)
Amine oxides (1)
Amino acids (20)
Amino acid-related (77)
Bile acids (24)
Biogenic amines (10)
Carboxylic acids (8)
Catechols (3)
Cresols (2)
Dicarboxylic acids (25)
Fatty acids (39)
Hormones and related (5)
Indoles and derivatives (18)
Nucleobases (5)
Nucleobase-related (14)
Nucleotides (2)
Organic acids (16)
Phenolic acids (22)
Phenoxy compounds (2)
Polyamines (7)
Pyridinecarboxylic acids (6)
Sugars (7)
Tricarboxylic acids (3)
Vitamins and cofactors (9)

Lipid panel

Acylcarnitines (40)
Ceramides (29)
Cholesteryl esters (22)
Diglycerides (41)
Dihexosylceramides (9)
Dihydroceramides (8)
Hexosylceramides (20)
Lysophosphatidic acids (8)
Lysophosphatidylcholines (12)
Lysophosphatidylethanolamines (43)
Lysophosphatidylglycerols (10)
Lysophosphatidylinositols (15)
Lysophosphatidylserines (12)
Monoglycerides (12)
Phosphatidic acids (41)
Phosphatidylcholines (76)
Phosphatidylethanolamines (95)
Phosphatidylglycerols (64)
Phosphatidylinositols (53)
Phosphatidylserines (18)
Sphinganines and sphingosines (8)
Sphinganine and sphingosine phosphates (8)
Sphingomyelins (14)
Triglycerides (242)
Trihexosylceramides (6)

Are you interested in a solution for small molecules only or lipids only? Learn more about the MxQuant and LxQuant kits.

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Solving chronic disease with metabolomics

Alice Limonciel, Ph.D.

Chief Scientific Officer
biocrates life sciences gmbh, Innsbruck, Austria

Discover the MxP® Quant 1000 kit that was designed to address the pressing issue of complex chronic diseases with metabolomics. In this talk, you’ll learn all about the choice of the metabolites and pathways that came in the creation of this new standard of excellence. You’ll also see concrete examples of how to apply the kit to screen samples, leverage data and translate insights into the solutions you need for your research.

MxP® Quant 1000 kit ‒ Making the difference

Markus Langsdorf, Ph.D.

Product Manager
biocrates life sciences gmbh, Innsbruck, Austria

Get an in-depth look at the MxP® Quant 1000 kit technology from its product manager, who will demonstrate how you benefit from its validated methods, ready-to-use components, and AI-powered workflow manager. Learn how the extensive coverage combined with high analytical precision from minimal sample volume delivers deep biological insights for fundamental, pharmaceutical, and clinical research.

Metabolomic profiling of HIV-driven inflammation using the MxP® Quant 1000 kit

Chris Basting, MS

Scientist
University of Minnesota, USA

We investigated the mechanisms driving chronic inflammation during antiretroviral therapy (ART) in people with HIV (PWH) using the biocrates MxP Quant 1000 to deeply profile the plasma metabolome of PWH and healthy controls. Our goal was to identify potential interventions that can mitigate chronic inflammation and reduce the occurence of comorbidities in PWH.

MxP® Quant 1000 – One solution, many applications

Fundamental research

Holistic understanding of chronic disease mechanisms
Systems biology studies
Biomarker discovery
Population health | Cohorts
Metabotyping
Multiomics

Clinical | Pharmaceutical research

Prodromal biomarkers
Disease risk prediction
New drug targets
Patient stratification
Drug response prediction
Progression monitoring
Precision medicine

Consumer health

Personalized healthcare and nutrition
Health monitoring
Preventive measures
At-home sampling
Participatory medicine

Dedicated kits for metabolomics and lipidomics

For applications where only small molecules or lipids are needed, metabolomics and lipid panels are available as separate kits.

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“What really stands out to me is the comprehensive coverage of biomarkers and metabolic pathways the MxP® Quant 1000 kit offers. Gaining such a holistic view from a single assay is remarkable and provides a powerful foundation to better understand the molecular landscape of chronic diseases, cancer types, and other multifactorial conditions.“

Dr. Gernot Poschet

Managing Director, Heidelberg University, Metabolomics Core Technology Platform

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“biocrates MxP® Quant 1000 kit offers excellent coverage of microbiome-related metabolites like SCFAs and bile acids—far beyond what we had before. The lipid coverage of it is also a major plus, especially for our HIV-focused research.”

Chris Basting, MS

Scientist, University of Minnesota