Standardized, quantitative metabolomics kits

Analyze thousands of metabolites with quality-controlled profiling technology

Robust and reproducible results

Over the last decade, biocrates kit technology has emerged as the gold standard in quantitative metabolomics, offering new possibilities for the study of human and animal health and disease.

Quantitative, standardized and scalable results

Fully established methods for calibration and quantification

Quality and reproducibility proven in international ring trials

Easy-to-use kits with software and expert support

Superior insights through extensive metabolic pathway coverage

Certified for ISO 9001:2015
and ISO 13485:2016

Speak to an expert

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Featured in over 2000 publications

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1500+ quantitative datapoints

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Reference ranges for easier data interpretation

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20+ years of experience

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Developed by experienced scientists

MxP^®Quant 500 XL

The largest combination of lipids and small molecules for quantitative metabolic profiling in a single kit. Ready-to-use kit covers more than 1,000 metabolites from various biochemical classes. With more than 400 quantifiable metabolism indicators, covering hundreds of metabolic pathways, researchers will be equipped with the right solution for a more comprehensive understanding of health and disease.

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Testimonials

Our Metabolomics Core is involved in many long-term projects. Such projects require the generation of reliable and comparable data over a long period of time, so data quality is of paramount importance to us. We rely on the biocrates platform’s high-quality workflow and data analysis pipeline, which helped us eliminate variability and generate reproducible data. Their technology has also proven to be highly versatile and we could generate amazing insights in different indications using a wide spectrum of sample matrices (e.g. biofluids, tissues, cells). Therefore, I highly recommend the biocrates platform to any researcher looking to improve their data quality or just getting started in metabolomics.

Dr. Gernot Poschet
Executive Director, Metabolomics Core Technology Platform, Heidelberg University & German Cancer Research Center

biocrates’ team of experts is highly professional, the analytical team is meticulous and knowledgeable about their workflow from sample prep to data analysis. The data analysis solutions brought me the efficiency and enabled me to focus on result interpretation for my research program. I am confident in continuing work with the biocrates team for my discoveries in future studies.

Ru Wei, PhD
Scientific Director, Proteomics, Chemical Biology & Proteomics, Biogen, USA

One challenge we face in clinical research is the limitation of the number of precious samples and the unique nature of each sample. It can be difficult to acquire matched controls for every study. We tested the QMDB and the various filter options matched well to study groups and the results aligned with our control groups. Reassurance by the QMDB helped us to verify that our results were within normal ranges and provide further power to our study.

Teodoro Bottiglieri, PhD
Director of Research, Center of Metabolomics; Baylor Scott & White Research Institute, USA

Our institute was looking for a standardized and validated approach to further expand our metabolomics portfolio. In general, LC-MS-based methods lack comparability and robustness. In addition, most self-developed or commercially available targeted approaches do not cover a broad spectrum of metabolites. Therefore, we use the MxP® Quant 500 XL kit on a routine base as a certified lab, because it is the most comprehensive solution for quantitative results on small molecules and lipids and complementary to our NMR-based metabolomics panel.

Dr. Sven Schuchardt
Head of Bio- and Environmental Analytics, Fraunhofer ITEM – Institute of Toxicology and Experimental Medicine, Germany

Accessible metabolomics

All-in-one metabolomics and lipidomics solution ready to use and easy to measure
User-friendly advanced analysis
Peace of mind with automated quality checks and guided expert support

Work smarter – not harder

1400 analytically validated biomarkers [µM] in a single assay
Robust, reproducible and scalable
Efficient set-up and processing, saving valuable time and resource
Global integration into laboratory network by cloud-based software solutions
Pricing based on cost per analyte to fit all budgets

Reliable results every time

Broad compatibility with data analysis tools
FAIR compliant with complete ownership of data
Compliant with data security protocols and General Data Protection Regulation (GDPR)
Benchmark against Quantitative Metabolomics Database (QMDB) standardized reference datasets

Technology brochure

Extensive pathway coverage

Quantifies up to 1019 metabolites from 39 biochemical classes from minimal sample amounts
Enables study of hundreds of relevant pathways with over 400 metabolism indicators
Provides a profound functional understanding of lipid and metabolite homeostasis

Easy and ready-to-use

Complete workflow from sample registration to data generation
No need for method development or optimization
Requires only 20 µL sample volume, applicable to various matrices

Quantitative and reproducible

Quantification based on internal standards and calibration curves
Standardized, quality controlled, and optimized for longitudinal studies
Proven high accuracy and reproducibility through cross-lab validation

Decipher disease complexity

Includes hundreds of metabolites related to healthy aging and neurodegenerative diseases
Applicable to different matrices such as plasma, blood, cells, tissues, urine, and many more

Application note

Application areas

Metabolism is a core function of all biological systems, which makes the study of metabolomics relevant in virtually every realm of biology
Most common application areas for biocrates kits are diseases (cardio-metabolic, neurological, different cancers, autoimmune), epidemiology, pharma, drug, clinical studies, microbiome, consumer health

Matrices

biocrates kits have been optimized for plasma but can be used in a wide range of matrices such as dried blood, serum, urine, feces, cells, tissues, cell medium, milk, cerebrospinal fluid
Contact us for application notes or publications on your matrix of choice

Species

Metabolites in biocrates kits are mostly widely conserved internal metabolites, therefore all eukaryotic species are relevant but also E.coli and other species can be metabolically characterized using biocrates kits
Examples are human, mouse, rat, cow, dog, zebrafish, yeast, C. elegans, E. coli and many more