Scientific presentation | biocrates life sciences gmbh https://biocrates.com Tue, 10 Dec 2024 13:34:56 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 https://biocrates.com/wp-content/uploads/2024/11/cropped-biocrates-favicon-150x150.png Scientific presentation | biocrates life sciences gmbh https://biocrates.com 32 32 Introduction to metabolomics in action https://biocrates.com/introduction-metabolomics-in-action/ Tue, 10 Dec 2024 13:34:03 +0000 https://biocrates.com/?p=275086

Speaker | Candace Guerrero, Ph.D.
Affiliation | University of Minnesota | Assistant Director of the Center for Metabolomics and Proteomics

Introduction to metabolomics in action

Part of the Webinar
Metabolomics in action

This lunch and learn event, sponsored by biocrates life sciences and hosted by Dr. Candace Guerrero, Assistant Director of the Center for Metabolomics and Proteomics at UMN, will feature presentations on cutting-edge research in metabolomics.

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]]> Investigating the stool and plasma metabolome of people with HIV https://biocrates.com/investigating-the-stool-and-plasma-metabolome-of-people-with-hiv/ Tue, 10 Dec 2024 13:20:36 +0000 https://biocrates.com/?p=275077

Speaker | Chris Basting, MS
Affiliation | University of Minnesota | Researcher 6

Investigating the stool and plasma metabolome of people with HIV

Part of the Webinar
Metabolomics in action

This lunch and learn event, sponsored by biocrates life sciences and hosted by Dr. Candace Guerrero, Assistant Director of the Center for Metabolomics and Proteomics at UMN, will feature presentations on cutting-edge research in metabolomics.

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]]> Metabolomics of sepsis and critical illness https://biocrates.com/metabolomics-of-sepsis-and-critical-illness/ Tue, 10 Dec 2024 13:10:36 +0000 https://biocrates.com/?p=275073

Speaker | Elizabeth Lusczek, Ph.D.
Affiliation | University of Minnesota | Associate Professor

Metabolomics of sepsis and critical illness

Part of the Webinar
Metabolomics in action

This lunch and learn event, sponsored by biocrates life sciences and hosted by Dr. Candace Guerrero, Assistant Director of the Center for Metabolomics and Proteomics at UMN, will feature presentations on cutting-edge research in metabolomics.

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]]> Fast-tracking interpretation and sharing of lipidomic data with standardized methods https://biocrates.com/interpretation-and-sharing-of-lipidomic-data/ Tue, 10 Dec 2024 12:44:31 +0000 https://biocrates.com/?p=274002

Speaker | Alice Limonciel, Ph.D.
Affiliation | biocrates life sciences gmbh | CSO

Fast-tracking interpretation and sharing of lipidomic data with standardized methods

Part of the Webinar
Lipidomics | From planning to interpretation and sharing

Although they can be measured with similar analytical methods, lipidomics and metabolomics datasets are often analyzed differently when it comes to statistics. These differences are primarily justified by the biology behind the molecules. In this talk, I will discuss specifically how the nature and structure of standardized lipidomic datasets influences data interpretation and sharing down the line. I’ll introduce tools and approaches to explore lipidomics, and discuss tips and tricks to make the most of this unique type of data. This talk will be especially aimed at scientists who are unsure how to analyze lipidomics and are looking for guidance.

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]]> Common pitfalls in clinical metabolomics: A guide from sample collection to data analysis https://biocrates.com/common-pitfalls-in-clinical-metabolomics/ Tue, 10 Dec 2024 12:40:53 +0000 https://biocrates.com/?p=274005

Speaker | Lisa Hahnefeld, Ph.D.
Affiliation | Goethe University Frankfurt | Institute of Clinical Pharmacology | Senior Scientist

Common pitfalls in clinical metabolomics: A guide from sample collection to data analysis

Part of the Webinar
Lipidomics | From planning to interpretation and sharing

Ensuring sample and data quality is crucial for reliable results in clinical metabolomics. However, strict sample stability protocols often conflict with practical clinical considerations. Additionally, integrating datasets with varying nomenclature, selectivity, or quantification strategies poses significant challenges. In this talk, I will highlight common pitfalls in the clinical metabolomics workflow and introduce useful tools to address these issues. This presentation is aimed at scientists involved in clinical projects who seek guidance on pre-analytical and dataset integration challenges.

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]]> Elucidating the impact of food-derived microbial metabolites on intestinal health https://biocrates.com/impact-of-food-derived-microbial-metabolites/ Tue, 10 Dec 2024 12:37:15 +0000 https://biocrates.com/?p=273992

Speaker | Josep Rubert, Ph.D.
Affiliation | Wageningen University | Division Human Nutrition and Health | Food Quality and Design | Assistant Professor

Elucidating the impact of food-derived microbial metabolites on intestinal health

Part of the Webinar
Benelux Webinar, October 2024 | Metabolomics in gut microbiome and nutrition

Dietary patterns encompass a diverse array of molecules foreign to the body. Upon ingestion and digestion, these nutrients undergo transformation by the trillions of microorganisms residing in our gastrointestinal tract, which in turn alters the chemical structures of these compounds, affecting their lifespan, bioavailability, and biological effects. Consequently, dietary patterns modulate the gut microbiome, influencing its functions and the production of gut microbial metabolites (GMMs). These GMMs, in turn, play a critical role in regulating gut homeostasis and determining the risk of intestinal disease. To address this complex challenge, we utilize various OMICS approaches. Our research first explores food-gut microbiota interactions by integrating in vitro models, in vivo studies, and omics techniques. We also replicate the gut microenvironment using 3D and 2D intestinal models that accurately represent intestinal homeostasis. Unraveling food-gut microbiome-intestinal interactions promises to pave the way for advancements in personalized nutrition.

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]]> Metabolomics meets microbiome – Investigating host response with quantitative metabolomics https://biocrates.com/metabolomics-meets-microbiome/ Tue, 10 Dec 2024 12:21:40 +0000 https://biocrates.com/?p=273999

Speaker | Alice Limonciel, Ph.D.
Affiliation | biocrates life sciences gmbh | CSO

Metabolomics meets microbiome – Investigating host response with quantitative metabolomics

Part of the Webinar
Benelux Webinar, October 2024 | Metabolomics in gut microbiome and nutrition

Besides directly measuring microbial metabolites, quantitative metabolomics enables the investigation of the effects of the microbiome on the broader metabolic picture of the host. In my talk, I will present examples of applications of metabolomics in various sample matrices and how to use this powerful tool to study the effects of the microbiome on the host.

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]]> Developing a baseline metabolomic signature associated with COVID-19 severity: Insights from prospective trials encompassing 13 U.S. centers https://biocrates.com/developing-a-baseline-metabolomic-signature-covid-19/ Tue, 10 Dec 2024 10:45:49 +0000 https://biocrates.com/?p=274996

Speaker | Kaifeng Yang
Affiliation | University of Minnesota | Ph.D. student

Developing a baseline metabolomic signature associated with COVID-19 severity: Insights from prospective trials encompassing 13 U.S. centers

Part of the Webinar
Metabolomics in action

This lunch and learn event, sponsored by biocrates life sciences and hosted by Dr. Candace Guerrero, Assistant Director of the Center for Metabolomics and Proteomics at UMN, will feature presentations on cutting-edge research in metabolomics.

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]]> Metabolomics in pharma – Bridging R&D translation barriers https://biocrates.com/metabolomics-in-pharma-bridging-rd-translation-barriers/ Tue, 10 Dec 2024 09:39:35 +0000 https://biocrates.com/?p=274901

Speaker | Marissa Jones, Ph.D.
Affiliation | biocrates life sciences gmbh | Business Development Manager

Metabolomics in pharma – Bridging R&D translation barriers

Part of the Webinar
Metabolomics in pharma – Bridging R&D translation barriers

In this lunch & learn event Marissa Jones shared insights on using metabolomics to uncover the “why” behind your research. Examine real-world case studies and see biocrates technology in action. Learn how metabolomics is making an impact in the pharmaceutical industry.

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]]> Standardizing targeted metabolomics studies using Agilent 6495 LC/TQ in concert with biocrates https://biocrates.com/standardizing-targeted-metabolomics-studies/ Mon, 09 Dec 2024 15:43:01 +0000 https://biocrates.com/?p=273990

Speaker | Hannah Florance, Ph.D.
Affiliation | Agilent Technologies | Field Applications Specialist

Standardizing targeted metabolomics studies using Agilent 6495 LC/TQ in concert with biocrates

Part of the Webinar
From zero to metabolomics hero

Metabolomics and lipidomics are areas of research which have grown hugely over the last 10-15 years. The focus is often on the non-targeted approaches. As knowledge of organism metabolomes and lipidomes has grown, so has the coverage and understanding of metabolic pathways and their networks. Researchers can now focus on key metabolites as markers of well curated pathways known to be impacted by many conditions and changes. This is enabling the emphasis to shift towards targeted approaches. This in turn, provides repeatable sample preparation and analysis with out-of-the-box solutions, such as the biocrates kit. With the new Agilent LC/TQ technologies, the number of metabolites which can be analysed concurrently continues to improve with shorter dwell times, faster polarity switching and increased sensitivity with the aid of improved signal: noise ratios. We show how the Agilent 6495 LC/TQ utilizes these attributes to be a leading multi omics platform for targeted metabolomics, lipidomics and proteomics. This webinar discusses how biocrates solutions such as such as the MxP® Quant 500 XL kit fits seamlessly into this platform.

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